For laboratory research use only. Not for human or veterinary use. Must be 21+.
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Single peptideMitochondrial & metabolic researchPre-order

MOTS-c

16-amino-acid peptide encoded in the mitochondrial genome.

$49$4.90/mg
  • Form: lyophilized (freeze-dried) powder, sealed vial
  • Certificate of analysis: manufacturer COA for every batch, posted before shipping — see certificates
  • Shipping: pre-orders ship by October 10 from the USA · free over $150
  • Payment: Cash App, PayPal, Venmo, Coinbase or Bitcoin — how it works

For laboratory research use only. Not for human or veterinary use.

Compound identity

CompoundFormulaMol. weightCASPubChem
MOTS-c C101H152N28O22S2 2174.6 g/mol 1627580-64-6 CID 146675088

Reference identity data from PubChem where listed. Each batch's purity data is on its certificate of analysis on the lab results page.

Research overview

MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c) is a 16-amino-acid peptide first described in 2015 1.

Mouse studies have examined its role in metabolic regulation and skeletal muscle, including direct binding to the kinase CK2 12. A 2023 review summarizes the field 3.

References

  1. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab, 2015. PubMed 25738459
  2. MOTS-c modulates skeletal muscle function by directly binding and activating CK2. iScience, 2024. PubMed 39559755
  3. MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation. Front Endocrinol (Lausanne), 2023. PubMed 36761202

Storage

Store sealed vials cold, dry and away from light. Lyophilized peptides are typically kept at −20 °C for long-term storage.

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